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Hidradenitis Suppurativa Decision Aid

  • 1. Introduction

    Learn more about hidradenitis suppurativa.

  • 2. My Options

    Read about available treatments.

  • 3. My Skin

    Learn about your hidradenitis suppurativa.

  • 4. My Values

    Express what is important to you.

  • 5. My Trade-offs

    Compare treatments with your values.

  • 6. My Decision

    Your results and next steps.

Introduction

What is a Hidradenitis Suppurativa Patient Decision Aid (HS PDA)?

A patient decision aid (PDA) is a tool to help patients make informed health care decisions with their health care providers.

This patient decision aid is developed specifically for people with hidradenitis suppurativa (HS) in order to:

  • help people learn more about HS;
  • provide information on available treatments for HS;
  • clarify what is important to you when selecting your treatment(s).

At the end of this PDA, you can bring a summary of your results to your health care provider to talk further about your treatment(s).

  • What is Hidradenitis Suppurativa?+

    Hidradenitis suppurativa (HS), also called acne inversa or Verneuil’s disease, is a long-term skin condition and disorder of hair follicles (Zouboulis, et al., 2015). HS results in inflamed and swollen lumps that can be itchy, painful, and lead to discharge (Alikhan, 2016). They are usually found at areas of the body where skin rubs together, such as the armpits, buttocks, thighs, groin, and underneath the breasts (Alikhan, 2016). Other affected areas may include the ears, stomach, neck, and chest.

    HS is not contagious. It is not due to poor hygiene nor is it caused by bacteria. However, secondary infections may arise in the HS affected area(s) (Deckers, van der Zee, & Prens, 2014).

    Please note that the following is a photo of hidradenitis suppurativa
    Example of Hurley stage I. Photo courtesy of Dr. Christopher Sayed.
    Example of Hurley stage I. Photo courtesy of Dr. Christopher Sayed.
    Please note that the following is a photo of hidradenitis suppurativa
    Example of Hurley stage I-II. Photo courtesy of Dr. Barry Resnik.
    Example of Hurley stage I-II. Photo courtesy of Dr. Barry Resnik.
    Please note that the following is a photo of hidradenitis suppurativa
    Example of Hurley stage III. Photo courtesy of Dr. Christopher Sayed.
    Example of Hurley stage III. Photo courtesy of Dr. Christopher Sayed.
  • How can Hidradenitis Suppurativa be diagnosed, graded, and classified?+

    Diagnosis of HS is based on clinical presentation. There are no specific lab tests for diagnosis.

    • There are several different systems for grading HS severity. Hurley staging is commonly used to assess extent of inflamed lumps, bumps, tunnels, drainage, and scars. It is comprised of the following three stages (Saunte & Jemec, 2017):
    • Stage I (very few non-scarring nodules and abscesses);
    • Stage II (interspersed nodules, abscesses, and tunnels that may leave scarring);
    • Stage III (large interconnected nodules, abscesses, and tunnels that may leave scarring and pus drainage).
  • Who gets Hidradenitis Suppurativa?+

    While HS affects up to an estimated 4% of the European population (Zouboulis, et al., 2015), this number is lower in North America (Zouboulis, et al., 2015; Lee, Alhusayen, Lansang, Shear, & Yeung, 2017; Canadian Skin Patient Alliance, 2017; Lachaine, Miron, Shear, & Alhusayen, 2016; Garg, Kirby, Lavian, Lin, & Strunk, 2017).

    People often develop HS during their early 20’s. However, HS can appear in children who have yet to reach puberty, although it is rare (Deckers & Prens, 2016).

    HS is more common in African-Americans than in Caucasians (Shah, 2005) and in women than in men, with a female-to-male ratio of 3:1 (Garg, Kirby, Lavian, Lin, & Strunk, 2017). Additionally, HS is more commonly diagnosed in people who are in their 3rd and 4th decades of life (Garg, Kirby, Lavian, Lin, & Strunk, 2017), although a diagnosis can be made in postmenopausal women.

  • What causes Hidradenitis Suppurativa?+

    Although the exact cause of HS is currently unknown, possible causes include genetic, hormonal, microbiological, and environmental factors (Ingram, et al., 2015).

  • What risk factors are commonly associated with Hidradenitis Suppurativa?+

    Some common risk factors that are associated with HS include:

    • a family history of HS, including a small percentage of families with mutations in gamma-secretase genes (Deckers, van der Zee, & Prens, 2014; Pink, Simpson, Desai, Trembath, & Barker, 2013);
    • obesity (Miller, et al., 2014; Zouboulis, et al., 2015);
    • smoking (Kohorst, Kimball, & Davis, 2015);
    • dysregulation of the immune system (Deckers, van der Zee, & Prens, 2014).
  • What conditions are commonly associated with Hidradenitis Suppurativa?+

    The presence of conditions associated with HS can vary between individuals. Some of the most common include, but are not limited to (Shlyankevich, Chen, Kim, & Kimball, 2014; Kohorst, Kimball, & Davis, 2015):

    • metabolic syndromes that are characterized by abnormal hormone levels, such as diabetes, dyslipidemia, and polycystic ovarian syndrome;
    • cystic acne and pilonidal disease;
    • heart disease, such as hypertension;
    • chronic inflammatory diseases, such as inflammatory bowel disease, arthritis, and dissecting cellulitis of the scalp;
    • small increased risk of some cancers, such as squamous cell carcinoma of the skin affected by HS and lymphoma.

    Consider undergoing regular screening for these conditions. Talk to your health care provider for more information.

  • How might Hidradenitis Suppurativa affect me?+

    People with HS often experience a reduced quality of life physically, socially, and emotionally (Gooderham & Papp, 2015). This may be due to the presence of uncomfortable symptoms, such as:

    • feelings of depression and embarrassment (Zouboulis, et al., 2015; Esmann & Jemec, 2011; Alavi, Anooshirvani, Kim, Coutts, & Sibbald, 2015);
    • interference of sleep schedules and certain movements/activities due to pain (Esmann & Jemec, 2011; Alavi, Anooshirvani, Kim, Coutts, & Sibbald, 2015);
    • avoidance of social situations and workplace opportunities (Zouboulis, et al., 2015; Esmann & Jemec, 2011);
    • physical intimacy issues with partners due to fear of HS visibility (Esmann & Jemec, 2011);
    • use of bandages to minimize malodorous discharge of lesions (Zouboulis, et al., 2015).
  • What should I do?+

    You should see a health care provider who can inform you of the severity of your HS affected area(s) and help guide you through available treatment options. Learning about these treatments may help you to take control over your condition and:

    • minimize your HS outbreaks;
    • make better informed decisions;
    • become an active participant in your own health.

    It is also recommended that you take care of yourself by:

    • carefully selecting loose clothing in order to reduce skin irritation (Esmann & Jemec, 2011);
    • paying attention to your moods and seeing your health care provider if you feel depressed or anxious (Shah, 2005);
    • maintaining a healthy diet, which may reduce HS symptoms (Danby, 2015);
    • avoiding wearing tight clothing in order to reduce skin irritation (Shah, 2005);
    • avoiding smoking, as it may worsen symptoms (Zouboulis, et al., 2015).

    You are also encouraged to seek in-person and online HS support groups.

  • How can I manage my pain?+

    The importance of pain management

    Pain is a frequent and often severe symptom of HS, as well as an important contributing factor to HS patients’ reduction in quality of life (Zouboulis, et al., 2015).

    Treatments for pain resulting from HS

    You should inform your health care provider and/or pain specialist what over-the-counter or alternative medicines you have tried, and discuss the different means/methods you have taken to reduce pain. Ask for their guidance before trying other treatments.

    Pain treatments for HS can be divided into first and second-line treatments (Horváth, Janse, & Sibbald, 2015).

    First-line treatments, which are to be tried first for pain resulting from HS, include (Horváth, Janse, & Sibbald, 2015; Scheinfeld, 2013):

    • Topical analgesics, which are pain medicines that can be applied directly on top of the affected skin area(s). These include lidocaine creams, some of which are available over the counter, and topical nonsteroidal anti-inflammatory drugs (NSAIDs).
    • Oral analgesics, which are pain medicines that are taken by mouth. These include oral acetaminophen and oral NSAIDs (e.g. acetylsalicylic acid, ibuprofen, naproxen).
    • A combination of both topical and systemic (oral) agents to increase the efficacy of pain management.

    If first-line treatments fail to relieve pain, you may wish to consult a pain specialist.

    Second-line treatments, which are to be recommended by a health care provider and/or pain specialist when first-line treatments are ineffective, include (Horváth, Janse, & Sibbald, 2015; Scheinfeld, 2013):

    • Oral anticonvulsants, which are pain medicines that are taken by mouth to help with nerve-related pain. These include pregabalin and gabapentin. Caution should be taken when taking these since their effectiveness will vary depending on the timing, severity, origin, and nature of the pain.
    • Oral opioids, which include codeine, hydrocodone, and morphine. These offer the highest level of pain relief; however, addiction and worsening of pain are possible side effects. Thus, they should be used with caution and only if the previous methods are ineffective after an adequate trial period.
  • How can I manage my wounds?+

    The importance of wound management

    There are two types of wound care in HS patients: day-to-day care of HS lesions and post-surgery care. The complete wound healing process in post surgical wounds varies based on the extent of the surgery, location, and HS patients’ general health. However, the time to complete healing can be shortened by adhering to a proper wound management regimen consisting of cleaning, treating, and bandaging, as well as taking antibiotics for secondary infections, should they occur (Wang, Wang, Sibbald, Alhusayen, Bashash, & Alavi, 2015). Additionally, the use of gentle cleansers can minimize the risk of developing irritant or allergic reactions (Wang, Wang, Alavi, Alhusayen, Bashash, & Sibbald, 2015).

    Optimal wound care management strategies should ultimately be personalized to the type and depth of the wound(s), cost of wound care relative to affordability, ease of application, absorbency, and management of odor. Talk to you health care provider and/or wound specialist regarding all methods used to treat wounds, including both typical and post surgical HS wounds.

    Methods for cleaning and treating wounds

    Warm compresses and baths may be used to clean minor wounds (i.e. early single lesions, no abscesses, minimal pain) and provide relief (Shah, 2005).

    Negative pressure wound therapy (NPWT), which uses a vacuum-assisted closure device, may help drain and seal open, large, and infected wounds resulting from surgical excisions (Alavi & Kirsner, 2015; Dini, Oranges, Rotella, & Romanelli, 2015).

    Support from a health care provider should be sought when dealing with moderate wounds (i.e. multiple recurrent lesions, abscesses with discharge, and/or moderate pain) and actively draining lesions (Shah, 2005).

    What to use as dressings

    The choice of dressing depends on several factors, such as the location and severity of the lesion(s) as well as its/their size, shape, and structure (Alavi & Kirsner, 2015). Therefore, there is currently no preference given to the use of a particular type of dressing for HS wound care. Nonetheless, dressings and bandages are especially important since they can protect wounds from irritation and absorb drainage (Alavi & Kirsner, 2015). The different categories of dressings include, but are not limited to:

    • Tubular net bandages to keep the dressings in place (Wang, Wang, Alavi, Alhusayen, Bashash, & Sibbald, 2015).
    • Atraumatic and absorptive foam dressings. These are costly and may be inaccessible despite their benefits in certain cases. Thus, they should be reserved for wounds that fail to respond to conventional dressings (Kazemi, Carnaggio, Clark, Shephard , & Okoye, 2018).
    • Absorptive dressings, such as hydrofiber dressings and superabsorbent pads for draining wounds (Dini, Oranges, Rotella, & Romanelli, 2015; Kazemi, Carnaggio, Clark, Shephard , & Okoye, 2018). Cheap alternative dressings include sanitary napkins and breast pads.
    • Antimicrobial dressings, such as manuka honey with silver alginate dressings (Dini, Oranges, Rotella, & Romanelli, 2015).
    • Advanced dressings, such as gentamycin-collagen sponges and platelet-rich plasma gel (Dini, Oranges, Rotella, & Romanelli, 2015).

    Your health care provider and/or wound specialist can provide more details regarding what dressing(s) to use for your wound(s).

    Patient-to-Patient Wound Care

    Wound care is important in managing HS and involves many variables and individual preferences. These can’t be adequately covered in this PDA. Talk to your dermatologist about your wound care needs and how they can help you select dressings and access appropriate resources.

Last Updated: July 2019